Here are just a few of the things I found useful;
When printing images from a CD don't use too thick or absorbant a card to make cutting out easier and to save on ink.
Once your images are printed, cut then out with big scissors trying to cut whole sides in one cut (- you get a straighter edge when not doing lots of little clips.)
When cutting out layers make sure non of the white surrounding card is visible on the cut image as it spoils the end image on the card.
Layers can be stuck together with a silicone glue or pads. I used Docrafts Stick- It glue and 1mm foam pads
- if you use deeper pads your card ends up very fat - I learned that!
Finally, you don't have to use all the layers printed if you don't want - again cards can end up too fat or too busy!
That's all I can think of for now, but feel free to add more tips as comments and I'll add them to my post.